PRP
PRP Procedure for IVF and Recurrent Implantation Failure
PRP is a concentrated blood product that contains a high percentage of platelets (biomolecules with natural healing and regenerative properties). To understand more, let’s take a step back and look at blood as a whole.
the platelets in PRP “contain multiple growth factors that normally help your body heal once your body has an injury somewhere in the body. They have been shown to help with accelerate healing and cause some level of anti-aging . . . that’s why it’s been used for the last 20 years in different areas of medicine.<br/>
PRP is used in a number of fertility treatments including IUI and IVF to assist with and improve egg quantity/quality and improve uterine lining thickness/enhance endometrial receptivity during an embryo transfer. It is most often used in those who have undergone multiple IVF cycles with a history of recurrent implantation failure (RIF), a condition in which multiple IVF transfers do not result in pregnancy despite high-quality embryos being transferred on multiple occasions. PRP is usually tried before turning to donor egg IVF, but may be used alongside donor egg cycles along with other supporting treatments focusing on reproductive immunology.
Intraovarian PRP
This procedure involves injecting 1-3 mls of PRP directly into the ovaries. This procedure is done under monitored anesthesia care by a physician. During the procedure a needle with the PRP is guided via ultrasound through the vaginal wall and into the ovaries where the PRP will then be deposited.
The procedure is ideally done one, two, and or three months PRIOR to the start of an IVF stimulation. It may be done at the time of an egg retrieval, but this would only be beneficial if the person were to undergo another IVF stimulation cycle.
High Volume Intrauterine PRP
During a high volume intrauterine PRP procedure, 8-10 mls are infused slowly into the uterus using an SHG catheter (with a balloon). During the process, the plasma will flow out of the uterus, through the fallopian tubes, and bathe the ovaries in the plasma. After the infusion process is complete, the individual will rest for 10 minutes with the catheter in place.